The Myeloscreen kits allow the identification of specific fusion genes, present in diseases of myeloproliferative nature. These kits are based on a new multiplex PCR design, which allows simultaneous detection of the presence of the different isoforms of the existing translocation, by means of a one-step quantitative RT-PCR reaction (qRT-PCR ONE-STEP), from RNA samples. This system has an analysis tool that facilitates this work and allows obtaining the results in a very simple way. Currently we have kits for PML-RARA and BCR-ABL, allowing the detection of all isoforms described.
Kit for the amplification and detection of the isoforms of BCR-ABL p190 (e1a2 and e1a3), p230 (e19a2) by real-time PCR